Abstract :
Introduction: Upper gastrointestinal tract disorders are one of the commonly seen entities in the clinical practice. Gastric carcinoma is the second most common cancer while oesophageal carcinoma is the sixth leading cause of the death worldwide. Histopathological study has been done to make a specific diagnosis or to follow the evolution of particular disease.
Aims and Objectives: To study histopathological distribution of various types of neoplastic upper GI lesions.
Materials and Methods: A retrospective study was conducted on 1,800 upper gastrointestinal biopsies performed at our hospital from May 2015 to April 2018. The biopsies were formalin fixed, and embedded in paraffin wax, sections were taken, stained with Haematoxylin & Eosin and examined
Results: The present study included 1800 patients, out of which 486 (27%) cases were found to be neoplastic. The mostly commonly encountered neoplastic lesions were -well differentiated Adenocarcinoma (8.5%), followed by poorly differentiated Adenocarcinoma (6%) and adeno-squamous carcinoma. The male to female ratio was 1.5:1.
Conclusion: Upper gastrointestinal endoscopy is safe, cost effective, relatively less invasive procedure and its co-ordination with histopathological examination is the gold standard for early detection of GI tract lesions especially neoplastic lesions and thus aiding in early treatment and management.
Keyword :
Endoscopy, Upper GI tract, Neoplastic lesions.