Abstract :
Hepato-protective effect of aqueous leaf-extract of Talinum triangulare on monosodium glutamate (MSG) induced hepatic damage in
albino rats. Liver damage was induced via oral intubation with MSG in two test groups; one group was not treated while the other
group was treated with aqueous leaf-extract of Talinum triangulare at 100,200 and 400 mg/kg body weight of rats twice for 1 week
respectively. One group was not induced and received distilled water only. The Liver enzymes activities were determined from plasma
transaminase activities of the rats. Twenty eight albino rats were grouped into A, B and C. Group B and C were further subdivided
into B1, B2, B3, C1, C2 and C3 respectively. Each group contained four rats. MSG was administered in all the B and C sub-groups
except group A (Positive control). Group B1-B3 (negative control) were not administered aqueous leaf-extract of Talinum triangulare
while groups C1-C3 were administered aqueous leaf-extract of Talinum triangulare and MSG orally twice daily for 1 week at varying
doses of 100, 200 and 400mg/kg body weight. The liver enzymes levels were determined using spectrophotometric method. The result
showed a significant (P
Keyword :
Talinum triangulare, MSG, Aqueous leaf-extract, Hepato-protective effect and transaminase activities and ALP Activity.