Volume :
2
Issue :
4
Abstract :
Eletriptan is a second generation triptan drug intended for treatment of migraine headaches. The prepared tablets were shown good compression parameters and they passed all the quality control evaluation parameters as per IP limits. All the formulations were prepared by direct compression method using 8mm punch on 8 station rotary tablet punching machine. The blend of all formulations showed good flow properties such as angle of repose, bulk density, tapped density. Twelve formulations F1-F12 were formulated and evaluated for various quality control parameters. All the formulations were passed the tests and the results were within limits. From the dissolution data it was evident that formulation F3 was found to be best formulation with maximum % drug release of 99.9 % in 6 minutes. Disintegration time of F3 was found to be 16.33 seconds.