Volume :
3
Issue :
3
Abstract :
Bilayer tablet of domperidone maleate formulated and evaluated with same drug in both layer immediate and sustained release biphasic dosage form. Domperidone maleate bilayer tablet prepared using the polymers like HPMC K100M, Metolose as a matrix forming agent and superdisintegrant like Croscarmellose sodium, sodium starch glycolate. Different effect of these polymer concentration and superdisintegrant were studied and evaluated by the dissolution study of prepared bilayer tablet along with weight variation, hardness, friability and content uniformity.