Abstract :
Fasciolosis is a disease caused by trematodes of the genus Fasciola. The parasite has worldwide
distribution, and is commonly referred to as “liver flukesâ€. The two most known species of Fasciola; namely, Fasciola
hepatica and F. gigantica are the causative agents of fasciolosis. The lifecycle of Fasciola entirely depends on snails
of the genus Lymnaea. The disease predominantly affects cattle, sheep and goats, and occasionally humans. In
animals, the disease is characterized by gradual loss of condition, progressive weakness, anaemia and
hypoproteinaemia with development of edematous sub-cutaneous swelling especially in the inter-mandibular space
and over the abdomen. Fasciolosis poses significant economic losses due to carcass condemnations, loss of
productivity and cost of drugs as a therapy each year worldwide. Fasciolosis is thought to infect about 17 million
humans worldwide and a further 180 million at risk of infection. The disease is cured by administration of
appropriate chemotherapeutics, especially, Triclabendazole (Fasinex), which is effective against all stages of
Fasciola. Prevention and control of fasciolosis should be targeted on drainage of stagnant water bodies and snail
control strategies.
Keyword :
Fasciolosis, Fasciola hepatica, Fasciola gigantica, Public Health Impact, Economic Impact