Abstract :
Nasal Route is an attractive method of vaccination and nasal drug delivery that provides
immediate absorption and the desired results. The Nasal route is best suited for those medications that can be
taken orally for diarrhoea or hepatic first-pass metabolism. The article reviews nasal body composition and
hydraulic spray formulation as pre-formulation studies that include PKa, water solubility, bright light,
lipophilicity. These pH adjuster or buffer systems are selected as excipient, processing and distribution of invitro
analytical test particles, Spray pattern, plume geometry, distribution of aerodynamic particle size .
Keyword :
Nasaldrug delivery, Nasal body composition, Nasal Spray, in-vitro characterization.