Abstract :
Sustained release Ketoprofen matrix tablets were prepared by direct compression method. The nature of the
polymer influences the physical and release characteristics of the matrix tablet. The hydrophobic polymer, Ethyl
cellulose has retarded the drug release from the tablet and the hydrophilic polymer, HPMC (15 cps) has release the
drug. While making the combination of both hydrophilic and hydrophobic polymers i.e HPMC and Ethylcellulose
with optimized ratio (F7) leads to sustained release of drug from matrix tablet for 12 hours was observed
Key words: Ketoprofen, HPMC (15 cps), Ethyl cellulose
Keyword :
Ketoprofen, HPMC (15 cps), Ethyl cellulose