Abstract :
Purpose: Bloodstream infections by bacterial pathogens are major cause of morbidity and mortality in developing countries. The aim of this study was to identify the bacterial pathogens causing bloodstream infections in certain areas of Dhaka, Bangladesh and determine their antibiotic susceptibility pattern according to age group.
Materials and Methods: A total of 6095 blood samples were collected from patients attending at Ad-din Women’s Medical College & Hospital from July 2019 to December 2020. All the blood samples were processed for culture using a BACT/Alert blood culture machine. Further identification & antimicrobial susceptibility tests were performed using standard microbiological procedures.
Results: Overall, 10.6% of the cultured blood samples were growth positive. Out of them, Gram-negative bacilli were predominant. Blood stream infection rate is highest among neonates, followed by the age group of 1-15 years, adult patients, with minimum rate observed among the age group of 1 month- 1 Year. Salmonella Typhi was the most frequently isolated among the Growth positive samples, followed by Coagulase negative Staphylococci (CONS), Acinetobacter, S. paratyphae, Staphylococcus aureus &
Klebsiella species. The most frequently isolated pathogens among Neonates were Coagulase negative Staphylococci Spp, and Acinetobacter Spp; whereas Salmonella Typhi was most commonly isolated pathogen among pediatrics and adult age group (p=
Keyword :
Bloodstream infection, BSI, Antimicrobial resistance, Neonatal Blood stream Infection, Multidrugresistance (MDR).