Abstract :
Background: Myocardial Pleural TB is one of the most frequent extra-pulmonary manifestations of tuberculosis. Extra
Pulmonary tuberculosis is the area of concern for the diagnosis of tuberculosis. Aim of this study is to estimate enzyme
Amylase levels in serum and pleural fluids of HIV seronegative exudative tuberculous pleural fluids and their possible role
in the diagnosis of tubercular pleural effusion. Methods: A total number of 100 patients were selected to do this study.
Selected individuals were randomly included in this study as cases and controls, 50 members each. The samples of blood
and pleural fluid were tested for amylase within the stipulated time, on the same day, to prevent the loss of analyte by CNPG
method. Results: Among Group I or Cases, the mean value of serum amylase and pleural fluid amylase was 53.044
and 77.122 respectively. Among Group II or controls, the mean value of serum and pleural fluid amylase was 49.508 and
63.238 respectively. Conclusion: Serum and pleural fluid Amylase levels indicate a coexisting pathology of pancreas,
gastrointestinal tract and malignancies. According to our study, diagnosing Tuberculous pleural effusion by assessing
amylase levels has less sensitivity and specificity.
Keyword :
Tuberculous Pleural effusion, Serum Amylase, Pleural Amylase