Abstract :
Brief Background: Chronic periodontitis is the inflammation of tooth-supporting tissues, caused by microorganisms present in the subgingival biofilm. Anti-infective therapy has been accepted as the cornerstone of periodontal treatment. The aim of the study was to evaluate the efficacy of amoxicillin and amoxicillin in combination with metronidazole as adjunct to scaling and root planing in treatment of chronic periodontitis.
Materials and Methods: A total of 52 participants having moderate to severe chronic periodontitis were included and divided into 2 groups. After thorough scaling and root planing, participants were prescribed Amoxicillin alone (Control group) or Amoxicillin + Metronidazole (Test group), three times a day, for a period of seven days. Plaque Index (PI), Gingival Index (GI), Probing Depth (PD) and Clinical Attachment Level (CAL) were assessed at baseline and 3 months interval.
Results: Significant differences were seen from baseline to 3 months in both test and control groups in terms of reduction in PI, reduction in GI, decrease in PD and gain in CAL (p
Keyword :
chronic periodontitis, amoxicillin, metronidazole, scaling and root planing