Author :
Neethu Mathew1,*, M. Sukumar2, T. K Ravi3, Arunkumar R4, Betty Carla5
Volume :
2
Issue :
1
Abstract :
Various N-[3-Chloro-2-(substituted)-4-oxazetidin-1-yl]-4-(1H-indol-3-yl) butanamide derivatives have been synthesized by the cyclo condensation of Schiff bases with tri ethyl amine and chloro acetyl chloride. The structures of the newly synthesized compounds have been established on the basis of their spectral data. All compounds were evaluated for ?-amylase inhibitory activity. All compounds investigated exhibited significant activity, comparable to that of the standard used.
Keyword :
N-[3-Chloro-2-(4-hydroxy-3-methoxy phenyl)-4-oxazetidin-1-yl]-4-(1H-indol-3-yl) butanamide, ?-amylase inhibitor.