Abstract :
Background: Mean platelet volume corresponds to average size of platelets and studies proved that large platelets are
enzymatically and metabolically more active and have prothrombotic potential. Chronic upper airway like marked nasal
septal deviation leads to higher Mean platelet volume and vice versa septoplasty operation lowers the volume of the
platelets over a period of time and hence reduces other associated comorbidities. Objectives: This study was done with an
aim to analyze the effect of Septoplasty on Mean Platelet Volume Levels in patients with Marked Nasal Septal Deviation.
Methods: A prospective study was done in a total of 50 patients who were selected from ENT OPD and ENT Ward of
Jawaharlal Nehru Medical College and Hospital, Aligarh Muslim University, Aligarh after proper history and examination.
Results: Data obtained from preoperative and postoperative blood investigation were analysed using paired t-test and it
was statistically proved that after Septoplasty, Mean Platelet Volume was significantly lowered in patients who had Marked
Nasal Septal Deviation. Conclusion: Septoplasty plays an important role in reducing the MPV value in cases with Marked
nasal septal deviation and thus other comorbid conditions can be prevented by doing septoplasty in these patients.
Keyword :
Nasal septal deviation; septoplasty; mean platelet volume.