Effect of Low Level Laser Therapy on the Rate of Orthodontic Tooth Movement in Humans and the Levels of TNF-? in Gingival Crevicular Fluid.


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Article type :

Original Article

Author :

Apoorva Shrinivasa Kamath, Ameet V Revankar, Anand K Patil

Volume :

5

Issue :

1

Abstract :

Aim: To appraise the effects of low level laser therapy (LLLT) on tumor necrosis factor-? (TNF- ?) levels in gingival crevicular fluid (GCF) and its concordance with rate of orthodontic tooth movement (OTM) if any. Materials and Methods: A split mouth investigation was done in 16 subjects in whom 150 g of force was used for individual retraction of each maxillary canine. A gallium-aluminum-arsenide diode laser (energy density, 8J/cm 2 ; wavelength, 940nm; power output, 100mW) irradiated only the experimental canine at 10 distinct points. The amount of canine retraction on the two sides was measured and compared. GCF levels of TNF-? was quantified using enzyme-linked immuno-sorbent assay (ELISA). Results: A significant elevation in the levels of TNF-? was noted on the experimental side (P Conclusion: The application of LLLT in conjunction with optimum orthodontic force accelerated the rate of OTM and elevated the GCF levels of TNF- ?.

Keyword :

Tumor Necrosis Factor; Gingival Crevicular Fluid; LLLT; ELISA.
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