Effect of Cold Application and Heparinoid on Periorbital Edema and Ecchymosis After Craniotomy: A Randomized Controlled Clinical Trial


Article PDF :

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Article type :

Original article

Author :

Serpil Yüksel,Neriman Akyolcu

Volume :

2

Issue :

2

Abstract :

This study was performed to determine the effect of cold application and heparinoid cream on periorbital edema and ecchymosis after craniotomy. The sample of this prospective parallel-arm, randomized controlled trial included 90 neurosurgical patients who underwent anterior craniotomy in two medical faculty hospitals of a university in Turkey. The patients were randomly assigned (1:1:1) to the cold application, heparinoid or control groups. Those patients in the cold application group received cold application with gel pack on their periorbital areas for 20 minutes per hour for three days beginning from the 3rd hour following craniotomy. On the other hand, the patients in the heparinoid group received heparinoid cream on their periorbital areas once at the 3rd and 9th hours after craniotomy and then four times/day at 6-hour intervals for three postoperative days. Periorbital edema and ecchymosis were evaluated for three days after craniotomy using Kara & Gokalan’s scale by blinded observers. In all the measurements after craniotomy, except for those at the 3rd hour, the periorbital edema score of the cold application group was significantly lower than those of both the heparinoid and control groups (p

Keyword :

Cold application; Craniotomy; Heparinoid; Periorbital edema; Periorbital ecchymosis
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