Abstract :
The current study deals with effect of aqueous extract of Piper betel leaves for testing of memory enhancing
activity on scopolamine induced amnesia in rats. Nootropics are the smart drugs that gained importance in treating
dementia, a major disorder in aged due to stress and also in Alzheimer disease. Cholinesterase inhibitors like,
Rivastigmine and Donepezil Nootropics drugs like, Piracetam are commonly used for improving memory, mood and
behaviour but their adverse effects have made their use limited. To treat memory disorders, in recent years, new
therapeutic agents, such as the steady impairment of memory in aging or in neurodegenerative pathology and even
lifestyle factors. In the treatment of various cognitive disorders, an effective therapy for the resolution of the cognitive
deficits is still needed and to discover the utility of traditional medicines is worthwhile. Piper betel leaves appears
as glossy and heart shaped, having a tremendous potential as a potent source for novel herbal drugs. It contains active
constituents mainly allylpyrocatechol, Chavibetol, Eugenol and Hydroxychavicol; which has many therapeutic uses
and supports the folklore. Because of the presence of wide range of flavonoids in the leaves of Piper betel, the
aqueous extract of the leaves was tested for the study of memory enhancing effect, against scopolamine induced
amnesia in rats.
Keyword :
Piper betel, Nootropics activity, Y-maze