Abstract :
This case control study had been carried out to evaluate antidiabetic and
antioxidant activities of Tinospora cordifolia (T. cordifolia; family:
Menispermaceae) against streptozotocin induced diabetes in experimental
rats to scientifically validate its use against diabetes. Ethanolic extract of T.
cordifolia stem extract and standard drug (glibenclamide) macerated with
aqueous gum acacia (2%, w/v) suspension and fed orally to streptozotocin
induced male adult diabetic rats of Charles Foster strain for 30 days.
Biochemical parameters in normal, diabetic control, standard (600µg/kg bw
p.o.) and treated (500 mg/kg bw p.o.) animals group were determined and
compared. Treatment of streptozotocin induced diabetic rats with ethanolic
extract caused significant (p
Keyword :
T. cordifolia, Natural Antioxidants, Post heparin lipolytic activity, Streptozotocin induced diabetes, plant antioxidant.