Volume :
5
Issue :
2
Abstract :
Introduction Diabetes mellitus (DM) is emerging as major health problem. There has been worldwide increase in prevalence of DM, especially in developing countries. With this increased prevalence of diabetes, drug utilization study of antidiabetic drugs is very useful from health care viewpoint. Aim The aim of study was to investigate the drug utilization pattern in type-2 diabetic patients. Methods A prospective observational study was carried out in Palakkad Diabetic Centre, Palakkad, for 6 months. Patients with type-2 diabetes and on drug therapy with or without co morbidities and complications were included. Patients’ socio-demographic and clinical data were noted in a pre-designed proforma. Data was analyzed by using SPSS version 16 and Excel 2007. Result Total 428 patient were enrolled with Mean± SD age 57.72± 10.8, were females are more prevalent (52%) and 77% had family history. Hypertension (26%) was most common co-morbid disease followed by dyslipidemia (21%). Totally 32% of patients were on Monotherapy and Metformin was commonly prescribed. In combination therapy, Glimepiride and Metformin (77%) were mostly consumed followed by Glibenclamide and Metformin (12%) there was no evidence of Polypharmacy. Conclusion Metformin was the most commonly used drug. The prescribing trend also appears to be moving towards combination therapy particularly two drug therapy. All insulin preparations were human insulin. . Incidence of diabetes has been found higher in female as compared to male and majority of the patients develop diabetes in the most productive years of their life .This study contributes to the growing body of literature on drug utilization research.