Volume :
1
Issue :
1
Abstract :
Objective: The objective of the current study was to develop rapid, accurate, reproducible, validated and economical Vierordt’s Method for the simultaneous determination of CEF and MOX in tablet dosage forms. Method: This method of analysis was based upon the absorption of drugs at wavelength maximum of each other. Two wavelengths of 289.10 and 295.10 nm were selected which are the λmax of two drugs for the development of the simultaneous equations. The absorbance of CEF and MOX were measured and the absorptivity values were determined at all the two selected wavelengths. Result & Discussion: The linearity was found to be 3-9µg/ml for CEF & MOX respectively. Recovery was in the range of 98 –102%; the values of standard deviation and% R.S.D. were found to be