Determination of anti-streptolysin


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Article type :

Original Article

Author :

Rounak Chahal, Shweta R Sharma, Anshuman Srivastava, Umar Farooq, Sudhir Singh, Vasundhara Sharma, Imran Ahamad

Volume :

7

Issue :

4

Abstract :

Introduction: The Group A beta hemolytic streptococcus has remained a major human infective agent for hundreds of years. Group 'A' beta hemolytic streptococcus related ailment and sequelae keep on affecting general public and national economy as they mostly influence kids and youthful grown-ups. Current research aimed to determination of anti-streptolysin –o titer in suspected cases of streptococcal infection. Objectives : Determination of anti-Streptolysin-O (ASO) titer in suspected cases of streptococcal infection. Materials and Methods: The measurement of ASO levels was done by semi-quantitative analyzer analyzer on photometric and colorimetric systems. 107 blood samples were taken in our study. This study was conduct in serological section of microbiology department of Teerthanker Mahaveer Hospital & research centre Moradabad. Results: A total 107 samples were tested in this study. Of these, 23(21.5%) were found to be positive for the presence of ASO having titre of >200IU/mL. Conclusion: This study will be useful to evaluate utility of sero-diagnosis in our catering population and found useful in early diagnosis and treatment of these pathogens. Treatment can be initiated at an early stage leading to reduction in complications and associated mortality.  

Keyword :

Rheumatic fever, Streptococcus, Rheumatic heart disease, Glomerulonephrits
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