Abstract :
Background: Preterm labor is still one of important cause of neonatal morbidity and mortality, many researches done to find the relationship with biochemical marker for early detection to promote the management plan to reduce the complication simple, cheap, available blood test applicable and acceptable by patients for that we choose complete blood test for this purpose.Aim and Objectives: To perform CBC in a group of pregnant women; follow women who have abnormal RDW-CV%, MPV/Fl through pregnancy to know whether they will go in for preterm labor.Materials and Methods: A 200 pregnant women were involved in the study, they divided into two group 100 term pregnant woman (37-40wk), and the others were preterm labor women (24- 36) weeks of gestation these patients collected from obstetric outpatient unit in hospital. gestational age was confirmed by menstral history and early ultrasound, preterm patient were examined by sterile speculum, preterm labor was considered if there was more than three cm dilatation of cervix and effacement ?80% or uterine contractions (?4 contractions/20 min), lasting in 30 seconds or more). Blood sample was taken from all patients in the laboratory unit before any treatment, send for CBC the mean platelets volume, and RDW data are recorded.Study Design: case control study done from January 2022, till December 2023.Result: Case control study involved 200 pregnant patients divided into two group, first group include 100 preterm labor (24-36weeks), and second group include 100 control term patient (37-40 week), When compared the result of complete blood count of patients it’s revealed significant difference of RDW-CV% between preterm and term group (P-value 0.0001), mean platelet volume also show significant difference the P-value was 0.004)Conclusion: RDW-CV% and MPV/Fl can be used as a predictor of preterm labor.
Keyword :
Platelets mean volume, Red cell distribution width, Preterm.