Volume :

5

Issue :

1

Abstract :

The Aim of the present study is to Design and Evaluate Edible gel (EG) loaded with Alendronate drug. The Bisphosphonate called Alendronate used for osteoporosis and several other bone diseases. Ten Formulation (EG1-EG10) of EG was prepared by varying concentrations of Gellan Gum (0.1-0.5%), 0.3% and above the concentration of polymer showed good physical and Rheological properties. Optimized formulation among EG was EG8 with no syneresis showing 99% drug release with good consistency and viscosity increasing the mouth feel. Based on the stability of EG at room temperature and also due to its high patient compliance based on appearance and ease of administration, EG was preferred as better dosage form for geriatrics and paediatrics.