D, L Glyceraldehyde- Will it be an effective Antiglycolytic Agent?


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Article type :

Original Article

Author :

Udaya Kumari Ganapathy, Nagendran Ramachandran

Volume :

3

Issue :

4

Abstract :

Aim: This study aimed to compare the effectiveness of D, L Glyceraldehyde (GLY) with Plain Sodium Fluoride (NaF) as an antiglycolytic agent and its interferences in the estimation of Serum creatinine by Modified Jaffe?s method and Serum Sodium and Potassium by ion selective electrode(ISE) method. Materials and Methods: Eighty random blood samples were collected from the OP patient after obtaining explicit consent. Serum Glucose, Creatinine, Sodium and Potassium were estimated in all the three tubes and the results were compared across. Statistical Analysis: ANOVA test was done to compare the analytical values obtained from all the three tubes. Results: Mean Glucose concentration in Plain Tube with Clot activator (PTC), NaF tube and the GLY tube were 142.25 mg/dl, 124.41mg/dl and 139.23mg/dl respectively. p-value for GLY tube vs NaF was 0.483, GLY tube vs PTC was 0.970 and NaF vs PTC was 0.349(p value < 0.05 considered significant). There was Positive interference with creatinine measurement by modified Jaffe’s method (p

Keyword :

D, L Glyceraldehyde, Plain tube with clot activator, Sodium Fluoride, Antiglycolytic agent, Glycolysis, Glucose