Abstract :
Background: Maintaining corneal wound integrity is an important goal in corneal perforations resulting from either traumatic or non- traumatic etiology. Tissue adhesives (TA’s) are group of synthetic or naturally occurring compounds, which helps in wound reconstruction and have emerged as alternatives to conventional sutures.
Aim: Our study aims to evaluate the efficacy N- butyl cyanoacrylate TA in corneal perforations following infectious keratitis by assessment of its morphological and functional outcome.
Materials and Methods: A prospective observational study conducted over a period of 6 months on 42 eyes of 42 patients with perforated corneal ulcer, fulfilling the inclusion criteria, presenting to our outpatient department. A standard technique was used to apply TA to the site of perforation under topical anaesthesia in all patients and they were followed-up for a period of 6 weeks. Data analysis was done using SPSS software (Version 22) and P value calculated by Pearson Chi-square test (Fisher exact test). P- value < 0>
Results: Morphological outcome in this study showed statistically significant relationship with causative organism and size of the perforations (p
Conclusion: TA’s works well when the corneal perforation is
Keyword :
Corneal perforation, Tissue adhesive, N butyl cyanoacrylate