Correlation of various histopathological lesions of prostate with serum prostate specific antigen and gleason grading


Article PDF :

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Article type :

Original Article

Author :

Dharamveer Sihag, Preeti Laddha

Volume :

8

Issue :

2

Abstract :

Introduction: Present study was conducted to determine the age distribution of patients with prostatic lesions, prevalence of distribution of various prostatic lesions and to study correlation of histopathological types of prostatic lesions with prostate specific antigen (PSA). Materials and Methods: A total 246 prostatic needle biopsies from patients of all age groups were included in the study. After studying the histopathological features, the diagnosis of various types of prostatic lesions was made and Gleason’s scoring was done in cases of prostatic carcinoma. Subsequently, a correlation was made between the histopathological diagnosis and serum PSA level. Results: The Mean±Sd of age is 69.7±9.9 years. In pure inflammatory lesions, LGPIN, HGPIN, BPH, and BPH with prostatitis majority had PSA level Conclusion: Histopathological diagnosis and grading plays an important role in the management of prostatic cancer. For satisfactory management of patient, a high degree of the awareness of the advances along with team approach has become imperative.

Keyword :

 BPH, LGPIN, HGPIN, PSA, Pure inflammatory lesions.
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