Abstract :
Diabetic Nephropathy in the long run leads to end Stage Renal Disease (ESRD). Serum Creatinine and
Serum Urea are recognised as ideal markers to co-relate the progression of diabetic nephropathy. Diabetic
Nephropathy is clinically diagnosed with decrease in Glomerular function rate (GFR), probability of
hypertension, cardiovascular diseases and morbidity or mortality caused due to it. The early detection
of an imbalance in the level of Urea and Creatinine levels can assist in the diagnosis and prevention of
Diabetic Renal diseases and its progression. In this study, the period of the commencement of Diabetes and
its severity is intensely correlated with an abnormal level of Urea but not so with that of Creatinine. While
Creatinine is regarded as greater sensitive index of kidney function than Urea and hence this justifies as the
requirement for a perfect filtration marker.
Keyword :
Diabetic nephropathy, ESRD-End stage renal disease, Serum urea, Serum Creatinine, Diabetes, GFR-Glomerular function rate, Type 2 diabetes, Diabetes mellitus Transasia.