Congenital Candidiasis In A Newborn


Article PDF :

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Article type :

Case report

Author :

Shrabani Mandal *, Mukut Banerjee*, Asim Kumar Mallick**

Volume :

7

Issue :

2

Abstract :

Congenital candidiasis (CC) is an extremely rare disease with less than 100 cases being reported in the literature. It presents within six days of life with manifestations ranging from localized skin disease to systemic involvement in the form of respiratory distress, sepsis with hepatospenomegaly, and death. We report a neonate who presented with diffuse pustular eruption on erythematous background involving head,face, trunk, and palms at birth. Candida albicans was identifi ed in 10% potassium hydroxide (KOH) smear and culture from the pustules. Intrauterine infection by candida may give rise to this condition and it differs from neonatal candidiasis, which manifests as thrush or diaper dermatitis. Intravenous fl uconazole and topical ketoconazole were given and the condition improved completely in two weeks. CC is rare and needs to be differentiated from other conditions presenting with pustular lesions at birth in order to avoid complications. Early diagnosis and prompt treatment of this condition is important as untreated cases carry a significantly high mortality rate of 8- 40%.

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