Abstract :
Diabetes is one of the major challenging diseases as it is associated with other health complications including Atherosclerosis (narrowing of blood vessels), Heart diseases, Neuropathy (nerve damage in limbs), and Hypertension (high blood pressure). Its prevalence has been precarious since the last decade. Researchers have been trying hard to find the best remedy for diabetes since the last century and have developed a whole range of drugs of various chemical classes to control the mortality rate. Antidiabetic drugs synthesized during the last century are classified into three stages in the present review article and certain examples with their structure, mode of action, and applications are briefly discussed in the article. The future aspect, drug of choice, and success rate have been discussed as well.
Keyword :
Diabetes, Antidiabetic agents, Hypoglycemic agents, Insulin, Sulfonylureas