Abstract :
Introduction: Urinary tract infections (UTIs) are the most commonly encountered bacterial infections in
healthcare with a spectrum of presentation ranging from benign symptoms of dysuria to life-threatening
pyelonephritis.
Aim: To isolate and identify the uropathogens causing community-acquired urinary tract infections and to
compare antimicrobial susceptibility pattern between biofilm and non-biofilm forming uropathogens
Materials and Methods: Midstream urine samples collected from 100 patients attending the OPD were
processed as per standard protocol. Antimicrobial susceptibility was performed for the uropathogens.
Biofilm production among the uropathogens was tested by the Tissue culture plate method.
Results: Out of the 100 patients with clinically suspected UTI significant growth of bacteria was seen
in 47%. E.Coli (40%) being the commonest uropathogen isolated and found to be sensitive to Ak (80%)
followed by Nitro (63%). Klebsiella spp and Pseudomonas exhibit a stronger biofilm-producing property.
Antimicrobial resistance was seen to be higher among biofilm producing uropathogens.
Conclusion: There is a direct correlation between biofilm production and resistance to antimicrobials
among the uropathogens comparing to non-biofilm producers.
Keyword :
CA-UTI, Uropathogens, Biofilm, Antimirobial resistance.