Abstract :
Spinal anesthesia has become most commonly used and choice of anaesthesia for surgeries on lower half of body after first planned spinal anaesthesia for surgery in man was administered by August Bier (1861–1949) on 16 August 1898, in Kiel(1), Germany. Coadministration of adjuvant drugs improve the quality and duration of anesthesia and analgesia and patient safety.
Aim of Study: To compare effects of Dexmedetomidine and Fentanyl as adjuvants to 3ml of 0.5% heavy bupivacaine injected intrathecally, in lower abdominal surgeries.
Design of the Study: Prospective randomized comparative study.
Materials and Methods: The study was approved by ethics committee and was conducted in 100 randomly selected patients posted for elective lower abdominal surgeries in the age group 18-60yrs belonging to both sex. Patients were divided into two groups- Group D (n=50) - received 5g Dexmedetomidine 3ml 0.5% heavy bupivacaine, Group F(n=50)-received 25µg Fentanyl 3ml 0.5% heavy bupivacaine, intrathecally respectively.
Observations and Results: In group D patients onset of sensory block was significantly faster 2.62±0.56 mins (p
and analgesic sparing effect in post operative period when compared to group F.
Conclusion: ?2 adrenergic agonist dexmedetomidine is a valuable adjunct to spinal anaesthesia it augments quality of spinal anaesthesia provides intraoperative sedation and hemodynamic stability.
Keyword :
Bupivacaine, Dexmedetomidine hydrochloride, Fentanyl citrate, Spinal anesthesia.