Abstract :
Background: Preservative free 2-chloroprocaine seems to be a better alternative to lidocaine and bupivacaine for day care procedures, because of its short duration of action. This study was designed to compare 2-chlorprocaine with low dose bupivacaine for saddle block in elective perineal surgeries on day care basis in terms of recovery and home readiness.
Aims: To compare 1% 2- chloroprocaine with 0.5% bupivacaine with respect to time taken to obtain discharge criteria from post-anaesthesia care unit (PACU) to post-operative ward, from hospital to home and time taken for ambulation and micturition.
Setting and Design: This is a prospective, randomized, double blind, parallel group clinical study, conducted on ASA class I and II patients undergoing elective perineal surgeries on daycare basis in MIMS teaching hospital, Mandya.
Materials and Methods: After obtaining approval from institutional ethical committee, a total of 100 patients were enrolled in this study. Saddle anaesthesia was achieved with 7.5 mg 0.5% hyperbaric bupivacaine (Group B, n = 49) or 1% 2- chloroprocaine 40 mg (Group C, n = 50). After completion of surgery, patients were monitored in PACU and postoperative ward using modified Aldrete’s score and PADSS. After discharging, patients were contacted at 24 hours and followed up for 7 days via telephone to assess potential complications of saddle block.
Statistical Analysis: Data analysis was done using IBM SPSS version 20. Chi-square test, Fisher’s exact test and independent t-test were used to compare the variables. P value of
Results: Mean time required to attain discharge eligibility from hospital in Group B was 296.24 min and Group C was 213.3 min with a difference of 83 mins (P < 0 xss=removed>
Conclusion: Chloroprocaine provides satisfactory anaesthesia with advantage of faster regression of block, early ambulation and micturition, and thus early discharge from the hospital.
Keyword :
Chloroprocaine, Perineal surgeries, Ambulation, Micturition.