Abstract :
Introduction: Rising prevalence of obesity represents rapidly growing threat for Indian subcontinent. Dyslipidemia in obesity accelerates the process of atherogenesis; though its occurrence can’t be underestimated in apparently normal individual lipids. This warrants need of precise measures to predict dyslipidemia beyond routine lipid parameters. Atherogenic Index of Plasma, Atherogenic Coefficient & Lipid Accumulation Product have gained attention in this regard.
Aims and Objectives: This cross sectional study aimed at assessing usefulness of calculated lipid indices over individual lipids as potential predictors of atherosclerosis in obesity.
Materials and Methods: The study enrolled 100 apparently healthy overweight & obese cases and 100 healthy controls. Fasting blood sample was collected for lipid profile parameters. Statistical analysis was done by SPSS software.
Results: The levels of TC(211.4 36.2/173.9 21.4), TAG (162.9 41.5/124.6 26.3), AIP (0.23 0.11/0.08 0.03), AC (4.3 1.4/2.7 1.1) & LAP (31.3 8.6/24.3 6.2) were elevated while HDL (41.7 9.2/ 52.2 8.3) levels were founder to be low in cases compared to controls (pCases having raised AIP and LAP outnumbered than those with atherogenic dyslipidemia.
Conclusion: Calculated lipid indices proved to be better than conventional lipid parameters as simple, sensitive & independent tools to screen high risk individuals for atherogenesis in obesity especially in Indian scenario with limited resources.
Keyword :
Obesity, Atherogenic index of plasma, atherosclerosis, Lipid accumulation product, Atherogenic coefficient.