Comparative study between hyaluronic acid & platelet rich plasma in treatment of knee osteoarthritis


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Article type :

Original Article

Author :

Chinmoy Das, Partha Pratim Das, Aniruddha Indra*

Volume :

10

Issue :

1

Abstract :

Background: Knee osteoarthritis (OA) is a prevalent degenerative joint condition. This study aims to compare the therapeutic potential of Hyaluronic Acid (HA) and Platelet Rich Plasma (PRP) in its management. Materials and Methods : A comparative study was conducted with patients receiving either HA or PRP injections. Outcome measures included VAS and WOMAC scores, safety profiles, patient satisfaction, and requirement for repeat injections. Results : PRP-treated patients exhibited superior improvement in VAS and WOMAC scores by the 12-month mark. Adverse reactions were minimal and comparable between groups. Notably, 92% of PRP recipients expressed a willingness for repeat treatment. PRP-treated patients also showcased prolonged therapeutic benefits, with fewer requiring subsequent injections. Conclusion: PRP outperforms HA in multiple domains, emphasizing its potential as a more effective treatment for knee OA.  

Keyword :

Knee osteoarthritis, Platelet Rich Plasma, Hyaluronic Acid, VAS score, WOMAC score