Abstract :
Introduction: Colorectal cancer (CRC), which comprises colon and/or rectum cancer, is a significant health problem and the world’s second most fatal cancer. Colorectal adenocarcinoma (CRA), can be divided into 4 grades according to Broder's criteria, i.e., well differentiated (I), moderately differentiated (II), poorly differentiated (III), and undifferentiated (IV). Currently, the TNM classification is considered the gold standard for the establishment of prognosis as well as deciding the type of treatment.
Aim: The aim of our study was to assess the incidence, gender preponderance, site, histological grading and staging of colorectal carcinoma in our hospital.
Materials and Methods: This is a retrospective study of 75 patients who were diagnosed as colorectal carcinoma from July 2022 to January 2024. The specimen of the cases were sent to our Department of Pathology, Acharya Shri Chandra college of medical sciences and hospital, Jammu for histopathological examination after resection.
Results: In our study we found out that the cases of colorectal carcinoma had a male preponderance with most cases ranging from age group 46 to 60. The most common site of occurrence was rectum and the most common histological grade diagnosed as per microscopy was grade ??, that is moderately differentiated adenocarcinoma. The highest number of cases were at Stage II, followed by Stage III.
Conclusion: There is an urgent need to look upon the alarming rate of colorectal carcinoma and understand its incidence, grading and staging for a better prognosis.
Keyword :
Colorectal carcinoma, Histological grading, AJCC TNM staging, Histopathology, Adenocarcinoma