Abstract :
Aim & Objective: To study the clinical profile and visual outcome of optic neuritis
Materials and Methods: Study population included patients who were clinically diagnosed as Optic neuritis at Department of Ophthalmology, Mamata medical college. A total of 30 cases were taken up for the study. Patients were examined in detail at presentation and treated with ONTT regimen and follow up done at 1 week, 1 month and 3 months.
Results: Most common age group affected was 20- 50 years with mean of 39.36yrs. Highest incidence was seen in age group of 41-50yrs which was found to be 36.7%. Higher incidence was seen in females. Females constituted 63.33%. Female to Male ratio was 1.72:1. Higher incidence of Papilitis was seen among males and RBN was more commonly seen among females. Incidence of retrobubar neuritis was slightly higher than papilitis. All presented with DOV. Pain was present in 56.66%. Loss of vision persisted more than 1 month in case of papilitis. BCVA after ONTT had very good improvement. After treatment majority had vision between 6/18-6/6 (46.38%) and was statistically significant. Also after 1month and 3 months majority had vision between 6/18-6/6 [60.52% and 64.56% respectively]. Only 3.23% had VA less than 6/60 after 3months. There was improvement in both colour vision and contrast sensitivity but was not statistically significant. Central and centrocaecal scotoma was most common visual field defect. MRI brain was done in only 11 patients due to financial constraints which revealed two MS and 3 cases of increased signal intensity in short segment of Optic nerve. The recurrence rate in our study was 6.66%.
Conclusion: The clinical profile of ON in Indian patients is different from that in the Western population. Unlike reported in the Western literature, Papillitis is as frequent as Retrobulbar neuritis in the Indian setup, with poorer visual outcome.
Keyword :
ON, ONTT, MS, Papilitis, Retrobulbar neuritis