Abstract :
Gingival overgrowth (GO) is a known side effect of calcium channel blockers. This study was conducted to determine the clinical assessment and prevalence of GO in patients treated with various antihypertensives A cross-sectional study of 50 patients taking antihypertensives was conducted in the department of Periodontology & Oral Implantology at Sri Guru Ram Das Institute of Dental Sciences & Research, Sri Amritsar. All patients were examined for the presence of GO using different indices: Miranda-Brunet (MB) index, Angelopoulos and Goaz (1972) (GO index). Probing depth and modified sulcus bleeding index were also measured. The frequency of GO was significantly higher in nifedipine-treated cases than other drug groups. Frequency of GO was 57.1% for nifedipine, 31.4% for amlodipine. Higher plaque and calculus were observed in patients taking calcium channel blockers. Patients taking antihypertensives were having poor oral hygiene. Patients taking nifedipine showed a higher frequency of GO. Gingival inflammation may act as a risk factor.
Keyword :
Calcium channel blockers, gingival overgrowth, Nifedipine, Amlodipine, Periodontitis.