Abstract :
Aim: To assess the cardiovascular risk factors and carotid intima media thickness in young Indian PCOS patients.
Materials and Methods : The study group included 25 PCOS patients who were diagnosed according to Rotterdam criteria and 15 ealthy controls who had normal menstrual cycles. The mean age and BMI in PCOS (age-22.33years, BMI 28.15.4 kg/m2) and ontrol (age 21.50.6yrs, BMI22.33.7kg/m2). In all these patients detailed clinical examination and anthropometry including height, eight were taken and BMI was calculated. Fasting blood glucose and serum insulin, lipids, high sensitivity C-reactive rotein (hs- CRP), follicle stimulating hormone, luteinising hormone, thyroid stimulating hormone, total testosterone were tested. OMA-IR was calculated according to formula FPG (mmol/l)* S. insulin (mIU/ml)/22.5. Carotid intima media thickness was easured n either side or mean of three readings taken as final value.
Results : Carotid intima media thickness was statistically significantly increased in PCOS patients compared to controls 0.6990.06 vs0.5580.05mm, p
Conclusion: Present study shows that patients with PCOS are at increased risk of atherosclerosis in young Indian women.
Keyword :
PCOS CIMT and hsCRP.