Volume :
4
Issue :
3
Abstract :
Carcinosarcoma of the uterus is an aggressive, rare biphasic neoplasm composed of malignant epithelial and mesenchymal elements believed to arise from a monoclonal origin. The principal treatment in early/locally-advanced carcinosarcoma is surgery. Because of its aggressiveness, it generally presents distant metastases at diagnosis. Adjuvant radiotherapy and chemotherapy have uncertain effect. Chemotherapy alone or associated with radiotherapy seems to improve disease free survival (DFS) and overall survival (OS) in stage III and IV UCS. No advantages in OS and DFS have been shown with radiotherapy alone. The present review summarizes and analyzes the most important features about this type of gynaecological cancer.