Author :
Mitalkumari A Gamit, Parimal H Patel, Hitesh Ahir, Hiral Kashanbhai Patel, Payal Soni, Bhavika C Patel, Mitalkumari A Gamit, Parimal H Patel, Hitesh Ahir, Hiral Kashanbhai Patel, Payal Soni, Bhavika C Patel
Volume :
11
Issue :
4
Abstract :
Background: Blood stream infections (BSI) are the major cause of morbidity & mortality among patients admitted in Intensive care units. So early identification of etiological agents & their antibiotic sensitivity pattern as well as & surveillance of etiological agents are useful to reduce mortality, improve clinical outcome of the patients & their prevention.Aim: To estimate the bacteriological profile of BSIs.Objective: To estimate Antibiotic sensitivity pattern of bacterial isolates of blood culture. Materials and Methods: A retrospective study conducted in microbiology laboratory at tertiary care hospital. Blood samples received in microbiology laboratory from ICUs. Blood culture samples were processed by standard microbiological techniques for isolation and identification of etiological agent. Antimicrobial sensitivity testing was performed according to Clinical laboratory Standard Institute guideline by using Modified Kirby-Bauer disk diffusion method.Result: A total number of 1184 blood culture samples from ICU received in bacteriology laboratory, out of which 217 were positive (18.32%) & 967 (81.67%) were negative. The most frequently isolated organism was Coagulase-negative Staphylococci (CoNS), which accounted for 28.98% followed by Enterococcus spp. and Pseudomonas spp. were also commonly isolated (13.04% each),& Acinetobacter spp. (12.07%). Both Acinetobacter spp. and Pseudomonas spp. have shown high resistance to multiple antibiotic classes.Conclusion: This study underscores the importance of continuous surveillance of bacteriological profiles and antimicrobial resistance patterns in ICU settings. The findings will aid in guiding empiric therapy, formulation of hospital antibiotic policies, and infection control strategies.
Keyword :
Blood stream infection, Antibiogram, ICU.