Abstract :
Plan: Biological prospective of 4-thiazolidinone
Prologue: 4-Thiazolidinones are derivatives of thiazolidine with a carbonyl group in the 4th position. Substitution on the 2nd, 3rd and 5th positions may be varied, but the greatest difference in the structure and properties is exerted by the group attached to the carbon atom on the 2nd position.
Methodology: 4-Thiazolidinones exhibited a broad spectrum of biological activities viz: anticancer, antimicrobial, antimycobacterial, antiviral, anti-HIV, analgesic, anti-inflammatory, antioxidant, anticonvulsant, antidiabetic, antimalarial, anti-hypertension, antiarrhythmic, antiprotozoal, hypolipidemic, etc.
Outcome: This study is an attempt to address the various biological potential of 4-thiazolidinone. Information provided in this manuscript may be useful for further investigations on this scaffold.
Keyword :
4-Thiazolidinone, chemistry of 4-thiazolidinone, Biological Potential