Abstract :
Barrett’s esophagus is premalignant condition in which the stratified squamous epithelium is replaced by metaplastic intestinal epithelium. The cause is usually long-standing gastro-esophageal reflux. Infection with Helicobacter pylori is also believed to play a role in this. The most significant complication is development of dysplasia with an increase in relative risk for development of adenocarcinoma 40–120 times.
Keyword :
Barrett’s esophagus, Metaplasia, Adenocarcinoma