Volume :

3

Issue :

1

Abstract :

Objective: To determine the microbiological profile and antibiotic susceptibility pattern of organisms isolated from diabetic foot ulcer in RMMCH Chidambaram Methods: This is a retrospective study with a review of the bacteriology results of specimens taken from 100 consecutive patients with diabetic foot infection at RMMCH in Chidambaram during the period of 2010 to 2011. The specimens were cultured using optimal aerobic and anaerobic microbiologic technics. Antimicrobial susceptibility testing to different agents was carried out using the diffusion method. Result: Staphylococcus aureus was the commonest isolate being recovered from 20% cases , including methicillin resistant staphylococcus aureus in 9 of 27(30) patients wounds. The organism isolated were pseudomonas aeruginosa(16%), proteousmirabilis (18%), klebsiella pneumonia(0.7%), Escherichia coli(13%), and klebsiellaoxytoca(0.6%).The antimicrobial suscepteblity testing , showed that vancomycin was the most effective against gram positive and amikoscin and ceftazidime was the most effective against gram-negative organism. Conclusion: Staphylococcus aureus, pseudomonas aeruginosa, proteous mirabilis, klebsieella pneumonia, Escherichia coli and Klebsiella oxytoca were the most common causes of diabetic foot infection. These wounds require use of combined antimicrobial therapy for initial patient.