Bacterial urinary tract infection in diabetes patients and evaluation for multidrug resistant organisms


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Article type :

Original Article

Author :

Reenu S.P, Girish Narayanaswamy, Ramesh Kumar Kushwaha

Volume :

8

Issue :

4

Abstract :

Background: Bladder infection exists as frequently occurring infectious disease in diabetic mellitus of all distinct age groups. Acute cystitis is recognised as higher frequency in person with diabetes. Urinary Tract infection is most familiar and widespread infection in world-wide. The frequency of urinary tract infection is at peak in patients with diabetic mellitus. Diabetic mellitus (DM) is a group of metabolic impairment characterised by hyperglycaemia resulting from defects in insulin secretion, insulin action or both. It’s a common disease that affects health in many ways and relevant problems one of the leading illness world-wide. Urinary tract infection medical aid experimental is less execution of urine culture and sensitivity. In the present study designed to find out occurrence of bacterial urinary tract infection, Multidrug resistant organisms, health risk and antimicrobial drug medication for UTI’s. Objective: To hypothesize the spectrum of uropathogens and the profile of antibiotic resistance pattern in both diabetic and non-diabetic patient with asymptomatic urinary tract infection. Materials and Methods: The research study was performed for the duration of 6 Months (April-September 2022) in Vydehi Institute of medical science and research centre (VIMS & RC) Whitefield Bangalore. Diabeticas well as non-diabetic patientsabove 18 years of age, from OPD and also admitted in General medicine department of VIMS & RC was considered. A total of 247 diabetic and non-diabetic urine samples from outpatients and inpatients was collected and processed in the microbiology laboratory. In accordance to principle of Clinical and Laboratory Standards Institute, the urine samples was collected and analysed. VITEK 2 Automated system analyser was used to determine Antimicrobial Sensitivity. Results: Bacterial Multidrug Resistant Organism isolates in diabetes mellitus with bacteriuria is 48 (53%). Bacterial isolates in non-diabetic mellitus with bacteriuria is 29 (17%). and is frequently isolated. Gram-negative bacteria are highly resistant to multiple drugs like, Amikacin, Nitrofurantoin, Ceftriaxone, Clavulanic acid, Cefpirome, etc moreover increasingly resistant accessible antibiotics. Conclusion: and was the most familiar isolated microorganisms.  

Keyword :

E.coli, Klebsiella pneumoniae was the most familiar isolated microorganisms
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