Abstract :
Background: Urinary tract infection (UTI) is one of the most common bacterial infection during pregnancy that lead to significant perinatal and maternal morbidity. In hospital it is the second most common infection after respiratory tract infection. Bacteria associated with urinary tract infection are common worldwide but spectrum varies with individual population. Many multidrug resistant bacteria have been reported and a significant increase in isolation rates makes them difficult-to-treat pathogen. The aim of the study was to detect the antibiotic susceptibility pattern of different urinary isolates from patients attending Obstetrics and Gynecology outpatient clinic.Materials and Methods: It is a retrospective study in Hind Lab Laboratory, Tertiary care Hospital, Assam. Urinary samples collected or received in the microbiology laboratory were processed following standard procedure. Organism isolated were tested for different antimicrobials and sensitivity pattern were observed by phenotypic and Vitek 2 compact system (bioMerieux).Results: Out of a total of 1847 urinary samples, 689 yielded pathogens of which 239 (34.6%) were Escherichia coli, 221 (32%) were Klebsiella pneumoniae, 105 (15%) were Enterococcus spp. Twenty-nine (52.7%) isolates were multi-drug resistant;. The other organisms isolated were, Enterococcus spp., Staphylococcus aureus, Acinetobacter baumanii, Candida spp, Enterobacter spp., Proteus spp. and Pseudomonas aeruginosa respectively. All the isolates shown varying degree of susceptibility to commonly tested antimicrobials.Conclusion: Thirty five (35%) per cent of urinary isolates were multidrug resistant bacteria. All of them shown varying degree of resistance pattern to different classes of antimicrobials. Cephalosporin and flouroquinolones group of drug had shown maximum resistance pattern. It is also important to limit antibiotic consumption and exposure. Hence, along with routine antimicrobial testing, tests for detection of drug resistance should be routinely incorporated for uropathogens.
Keyword :
Antibiotic susceptibility testing; Multidrug resistance, Obstetrics and Gynecology clinic, Urinary tract infection