Author :
Srinivas Bhat U, Mohandas Rai, Sharath Kumar Krishna, Rashmi Rao
Volume :
1
Issue :
1
Abstract :
Background: Mood or affective disorder is psychological manifestations, depression is now known as a complex disorder involving the whole body and the diagnosis of depression is based on a heterogeneous set of symptoms.
Objectives: To evaluate antidepressant activity of Areca catechu Ethanol Extract in Swiss Albino Mice.
Materials and Methods: Adult Swiss albino mice were selected and randomly divided in to five groups as control which received normal saline, standard which received Imopramine 10mg/kg and three test groups which received Areca catechu ethanol extract at the dose of 40, 80 and 160 mg/kg respectively. All the drugs were administered intraperitonially (0.1ml/10gm) 30 minutes hour before the experiment followed by testing with forced swim test and tail suspension test successively to note the duration of immobility with the observation as mean± SD and was compared with the control by using ANOVA followed by Dunnets test. p