Astudy on prognostic significance of neutrophil-lymphocyte ratio in patients with stemi


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Article type :

Original Article

Author :

Anurekha G, Nallathambi M*, Paranthakan C

Volume :

13

Issue :

2

Abstract :

Introduction: Atherosclerosis, the clinically manifested form of cardiovascular disease (CVD), mainly accounts for most deaths worldwide. Inflammatory disorders that elevate CVD risk have been associated with circulating inflammatory markers that encompass neutrophil-lymphocyte ratio (NLR), which could be employed as an economical prognostic tool for the diagnosis of the same. Aim: Hence, this study focused on assessing the extrapolative implication of NLR among ST-Elevation Myocardial Infarction (STEMI) patients. Materials and Methods: The observational study included 55 STEMI patients (Mean age – 52.08 years) at Thanjavur medical college (December 2015 to February 2016). The patients were delineated into two groups based on NLR values (high >3.0 and low Results: Among the 55 patients, the post-MI complication was observed in 44 subjects, among which 10% of them expressed a high NLR value. A notable proportion of patients displaying arrhythmia and LV dysfunction had higher NLR values. Conclusion: Henceforth, the study reveals the independent and vital prognostic association between NLR and atherosclerosis that could be designated as a reliable marker in the early diagnosis of the disease as well post MI complications.

Keyword :

Atherosclerosis, Inflammatory markers, arrhythmia, LV dysfunction, Post­MI complications