Abstract :
Background: Hyperlipidemia has been shown to be associated with Glaucoma as well as increased intra ocular pressure (IOP). We conducted a case control study to further study the association of Lipid profile with Primary Open Angle Glaucoma (POAG) in non-obese patients.
Materials and Methods: With the approval from Institutional Ethics Committee (ICE) and written informed consent, 100 adult patients were included in the case control study. The methods applied in the study adhered to the tenets of the declaration of Helsinki. 50 non-obese POAG patients of above 40 years aged were included as cases and another 50 without Glaucoma were taken as controls. Patients were further subjected to biochemical investigation of the serum lipid profile performed by Vitros 5600.
Results: Mean total cholesterol, triglyceride and low-density lipoprotein (LDL) levels were found to be significantly higher in non-obese POAG cases as compared to that in controls (p
Conclusion: The study demonstrated a relationship of serum lipid levels with risk of primary open angle glaucoma.
Keyword :
Primary open angle glaucoma (POAG), Hyperlipidemia, Cholesterol, Triglycerides, Hgh density lipoprotein (HDL), Low density lipoprotein (LDL).