Abstract :
Introduction: Increased Glycated Hemoglobin (HbA1c) is a crucial indicator for inappropriate or inadequate diabetes care in patients with type 2 diabetes since it indicates inadequate long-term glycemic control. Serum ferritin, an indicator of iron stores, can be elevated due to chronic inflammation or iron overload, conditions that are not uncommon in diabetes. G6PD (Glucose-6-Phosphate Dehydrogenase) deficiency, while less directly related to diabetes control, can influence oxidative stress and redox status, potentially affecting overall diabetic complications.Aims & Objectives: The study aims to investigate whether there is a significant correlation between Serum Ferritin, G6PD, and HbA1c in cases of type 2 diabetes mellitus and normal healthy controls.Materials and Methods: This cross-sectional analytical study was conducted in the Department of Biochemistry and Endocrinology at KPC Medical College. 42 patients, aged 18 to 80 years, with type 2 diabetes mellitus, diagnosed according to the American Diabetes Association (ADA) criteria, were selected as cases. All are newly diagnosed patients without any comorbidities. An equal number of age and sex-matched healthy individuals were recruited as controls.Results: Significant negative correlations have been observed both between G6PD and HbA1c [r = (-0.84), p
Keyword :
Glycemic control, Oxidative stress, Iron overload.