Assessment of Incidence and Prevalence of Prostate Cancer in Middle Aged Male Patients of Western Nepal Using Prostate-specific Antigen and Digital Rectal Examination that Underwent Prostate Biopsy


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Article type :

Original article

Author :

Suman Sharma

Volume :

10

Issue :

1

Abstract :

This study was conducted to evaluate the incidence of prostate cancer (PCa) in male patients with increased prostate-specific antigen (PSA), and normal or abnormal digital rectal examination (DRE) that underwent a prostate biopsy. From March 2018 to November 2018, a total of 98 consecutive males suspected of having PCa due to increased PSA levels underwent transrectal ultrasonography (TRUS)-guided sextant biopsy of the prostate. The total PSA (tPSA), demographic data, the incidence of PCa, benign prostate hyperplasia (BPH), and prostatitis were assessed. The patients were divided into two groups according to their PSA values (Group A serum tPSA level, 4–10 ng/mL; and Group B serum tPSA level, 10.1–20.0 ng/mL). Of the 98 biopsied cases, 56% had PCa, 23% had BPH, and 21% had prostatitis. The mean PSA and the age of the carcinoma group were significantly higher than those of the benign group (P < 0>10 ng/mL, TRUS-guided biopsy is indicated, whatever the findings on DRE and/or LUTS, since the PCa detection rate is high.

Keyword :

Benign prostate hyperplasia, digital rectal examination, lower urinary tract symptoms, prostate biopsy, prostate carcinoma, prostate-specific antigen
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