Volume :
4
Issue :
2
Abstract :
Methanolic extracts of Aloe vera, Bauhinia variegate, Centella asiatica, Cuscuta reflex, Chromalaena adarata, Cynodon dactlon, Myrica esculenta, Nyctanthes arbor tritis, Psidium guajava, Rhododendron arboretum, Ficus lacorpysus, Pyrus pashia, Bombax ceiba were evaluated for their total tannins and total phenolics. Among them, Bauhinia variegata, Myrica esculenta, Rhododendron arboreum, Pyrus pashia and Psidium guajava were found to have highest tannin content. These plants were further subjected to evaluate the antioxidant activity by DPPH assay. Bauhinia variegata, Rhododendron arboreum, and Myrica esculenta were formulated into 10% w/w ointment in the ratio of 1:1:2 respectively. In excision wound model, 9 days observation showed that wound was totally healed in herbal ointment treated rats while 2.72%, 4.5%, and 5.73% wound area was found remaining in Framycetin treated, blank and control group of rats, respectively. These traditional medicinal plants showed the significant wound healing activity in animal models, which justifies their use in traditional practice in Nepal.