Abstract :
Introduction: COVID?19 is caused by SARS?CoV?2 and spreads from person?to?person. Pregnant women continued to be vulnerable to COVID?19. Infant protection from covid-19 infection is primarily dependent on neonatal innate immune responses and maternally derived, transplacentally acquired antibodies. Our aim was to study trans placental passage of anti-SARS-CoV-2 antibody and the magnitude of natural passive immunity in infants born to mothers with covid 19.
Materials and Methods: Prospective observational study was conducted at Balchikitsalay of MBGH, RNT medical college, Udaipur, Rajasthan from June 2021 to December 2022. Mothers with history of covid-19 positive in past at time of delivery in our hospital[MBGH] and all infants [0 days to 12 months] delivered from covid positive mothers who fulfill inclusion and exclusion criteria were enrolled in study. Measurement of SARS Cov2 antibody titre (serum IgG) in mothers and infants at our central lab where this sample was analysed by electrochemiluminescence.
Result: Total 100 covid-19 positive mothers and their infants who fulfill inclusion and exclusion criteria were enrolled in study. Out of 100 infants, 59% were males and 41% were females. Out of 100 infants, 12 (12%) were found in age group of
Keyword :
Antibody titer, Covid-19, Infants, Infected mothers, Sars-cov-2, Vaccination